澳门新葡8455最新网站-点击进入

马淇 助理研究员 阅读次数:

马淇 博士

助理研究员

联系电话:010-6275-7095

E-mail: maq@pku.edu.cn

通讯地址:澳门新葡8455最新网站-点击进入英杰交流中心339E 100871

2002-2006就读于澳门新葡8455最新网站-点击进入生命科学学院,获学士学位;2006-2011就读于中国科学院动物澳门新葡8455生物膜国家重点实验室,获博士学位;2012-2013在宾夕法尼亚大学费城儿童医院Douglas Wallace实验室从事博士后研究;2013年3月起就职于澳门新葡8455最新网站。在过去的工作中一直从事于线粒体的研究,目前主要的研究兴趣有:1、线粒体蛋白功能与蛋白质组学;2、线粒体超氧炫及其下游信号通路;3、针对线粒体相关疾病的小鼠模型。

代表论文:

1. Ma Q*, Liu L, Chen Q. Reactive Oxygen Species, Mitochondrial Permeability Transition and apoptosis. Acta Biophysica Sinica. 2012;28(7):523-536. (* corresponding author)

2. Ni B, Ma Q*, Li B, Zhao L, Liu Y, Zhu Y, Chen Q. Phenylarsine oxide induces apoptosis in bax- and bak-deficient cells through upregulation of bim. Clinical Cancer Ressarch. 2012;18(1):140-151. (* co-first author)

3. Liu L, Feng D, Chen G, Chen M, Zheng Q, Song P, Ma Q, Zhu C, Wang R, Qi W, Huang L, Xue P, Li B, Wang X, Jin H, Wang J, Yang F, Liu P, Zhu Y, Sui S, Chen Q. Mitochondrial outer-membrane protein fundc1 mediates hypoxia-induced mitophagy in mammalian cells. Nature Cell Biology. 2012;14(2):177-185.

4. Ma Q, Fang H, Shang W, Liu L, Xu Z, Ye T, Wang X, Zheng M, Chen Q, Cheng H. Superoxide flashes: Early mitochondrial signals for oxidative stress-induced apoptosis. Journal of Biological Chemistry. 2011;286(31):27573-27581.

5. Zhu Y, Lu T, Wang R, Huang L, Ma Q, Zhao L, Gao P, Lei X, Ni B, Lin J, Hao X, Chen Q. Functional conversion of Bcl-2 into a pro-apoptotic molecule to regulate mitochondrial cytochrome c release. Chinese Bulletin of Life Sciences. 2011;23(11):1076-1080

6. Zhao X, Liu Y, Ma Q, Wang X, Jin H, Mehrpour M, Chen Q. Caveolin-1 negatively regulates trail-induced apoptosis in human hepatocarcinoma cells. Biochemical and Biophysical Research Communications. 2009;378:21-26

7. Nan B, Zhou Y, Liang Y, Wen J, Ma Q, Zhang S, Wang Y, Su X. Purification and preliminary x-ray crystallographic analysis of the ligand-binding domain of sinorhizobium meliloti dctb. Biochimica et Biophysica Acta. 2006;1764:839-841